Ultra High Performance Liquid Chromatograph Method Scouting System
Enhancing Method Development Efficiency by Nexera Method Scouting
In a typical method
scouting procedure, data is collected using a number of mobile phase and column
combinations. Analyzers switching manually between these combinations are
limited by the number of work hours in a single day, making it impossible to
perform method scouting efficiently. The Nexera Method Scouting System is
capable of automatically investigating up to 96 combinations of mobile phases
and columns, without such time restrictions, thereby significantly improving
method development productivity.
Method Scouting
Workflow
・Method
Scouting Workflow
↓
・Analysis
conditions settings
(Mobile
phase and column selection)
↓
・Analysis
(Performed
automatically)
↓
・Comparison
and evaluation of chromatograms
↓
・Method
establishment
The Nexera Method Scouting System achieves stable data acquisition by adopting the newly developed FCV-34AH (100 MPa pressure resistance) high-pressure-resistant column switching valve and manifold. In addition, with auto-purging, mobile phase equilibration times are reduced by purging the mobile phase inside the autosampler, which means a faster method scouting workflow
Comparison and
evaluation of chromatograms
Multi-Data Report* enables quantitation in order to search
the data obtained from method scouting for optimal data. With Multi-Data
Report, numerical data and graphs can be created, utilizing Microsoft Excel,
from calculations based on the degree of separation and the number of peaks. As
a result, in addition to visual comparison of chromatograms, determinations can
be made based on quantitation of determination standards.
Multi-Data Report*
(LabSolutions Multi-Data Report)
Method establishment
Method scouting
performed by UHPLC, followed by transfer to conventional conditions
Sample Application
Peak tracking via
interlink with LC/MS
An LC/MS can be used as the Nexera Method Scouting System
detector. Mass spectral data from LC/MS systems support peak component
specification. As a result, peaks can be identified without re-analyzing
individual components.
ĐẠI DIỆN ĐỘC QUYỀN SHIMADZU TẠI VIỆT NAM
Hotline: 0902 550 957
TRỤ SỞ TẠI TP. HỒ CHÍ MINH: 6A-6B Nguyễn Cảnh Chân, Quận 1, TP Hồ Chí Minh
VPĐD TẠI TP. HÀ NỘI: 12-14 Cửa Nam, Quận Hoàn Kiếm, TP. Hà Nội
Email: huynhthanhmt06@gmail.com
Website: shimadzu-vietnam.com